Plant Transcription Factor Database
Previous version: v3.0
Gossypium hirsutum
EIL Family
Species TF ID Description
Gh_A02G1256EIL family protein
Gh_A03G2063EIL family protein
Gh_A05G0554EIL family protein
Gh_A05G0871EIL family protein
Gh_A06G0989EIL family protein
Gh_A08G1750EIL family protein
Gh_A13G1864EIL family protein
Gh_A13G2005EIL family protein
Gh_D03G0396EIL family protein
Gh_D03G1810EIL family protein
Gh_D05G3883EIL family protein
Gh_D06G1178EIL family protein
Gh_D07G1670EIL family protein
Gh_D08G0312EIL family protein
Gh_D08G2099EIL family protein
Gh_D12G2800EIL family protein
Gh_D13G2252EIL family protein
Gh_D13G2404EIL family protein
Gh_Sca006457G01EIL family protein
EIL Family Introduction

The gaseous phytohormone ethylene regulates various processes related to growth, development, and stress response of higher plants. A largely linear pathway of ethylene signaling was revealed by a number of molecular genetic studies. In the pathway, Ethylene-insensitive3 (EIN3) and EIN3-like (EIL) proteins are the key transcription factors. The EIN3/EIL proteins were shown to regulate expression of the GCC-box-binding transcription factors, ethylene-response factors. It is known that the phenotype of the Arabidopsis thaliana EIN3 (AtEIN3)-deficient mutants, e.g. long seedlings in the presence of ethylene or its precursor, is suppressed by overexpression of Arabidopsis EIL1 (AtEIL1) or EIL2 (AtEIL2), indicating the functional equivalence of these proteins.

In the present study, a region corresponding to the major DBD of the EIN3/EIL transcription factor family, which is the key factor in the ethylene signaling, was identified. The isolated domain exists in a monomeric form and retained the sequence specificity for the DNA binding. The structure determined by NMR spectroscopy consists of five alpha-helices, packing into a novel fold dissimilar to known DBDs. An NMR titration analysis suggested that a region including the key mutation site, ein3-3 site, was shown to be involved in DNA binding.

Yamasaki K, Kigawa T, Inoue M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Tomo Y, Terada T, Shirouzu M, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.
J Mol Biol, 2005. 348(2): p. 253-64.
PMID: 15811366